Description

2,2'-Anhydro-3'-Deoxy-5-Ethyluridine is a specialized nucleoside analog derivative, a key intermediate in the synthesis of modified nucleic acids and antiviral compounds. Its unique anhydro structure makes it a valuable building block for pharmaceutical research and development, particularly in creating novel therapeutic agents. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors focused on nucleoside-based drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Antiviral Drug Research: Used in the development and study of potential therapeutic agents targeting viral polymerases.
• Modified Nucleoside Synthesis: Serves as a precursor for creating a variety of 2',3'-dideoxynucleoside derivatives with altered sugar moieties.
• Biochemical Research: Employed in studies investigating nucleic acid metabolism, enzyme inhibition, and structure-activity relationships (SAR).
• Process Chemistry & Scale-Up: Used in the development and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Fine Chemical Production: A key raw material for custom synthesis and the manufacture of high-value specialty chemicals.

Basic Information

Product Name	2,2'-Anhydro-3'-Deoxy-5-Ethyluridine
CAS No.	133177-88-5
Molecular Formula	C11H14N2O5
Molecular Weight	254.24 g/mol
Synonyms	5-Ethyl-2,2'-anhydro-3'-deoxyuridine; 2,2'-Anhydro-5-ethyl-3'-deoxyuridine; 3'-Deoxy-2,2'-anhydro-5-ethyluridine; 5-Ethyl-2,2'-O-cyclouridine; 2,2'-Anhydro-3'-deoxy-5-ethyl-1-β-D-arabinofuranosyluracil; NSC 382501; Anhydro-5-ethyl-3'-deoxyuridine
EINECS	Contact for details

Quality Control

Our 2,2'-Anhydro-3'-Deoxy-5-Ethyluridine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry guidelines to support our customers' quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.