Description

H-Lys(Boc)-Obzl·Hcl is a protected amino acid derivative, specifically the benzyl ester hydrochloride salt of Nε-Boc-L-lysine. This compound serves as a crucial building block in solid-phase and solution-phase peptide synthesis, enabling the controlled elongation of peptide chains. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutic peptides and biochemical probes.

Application

• Peptide Synthesis Intermediate: A key raw material for the controlled incorporation of lysine residues into custom peptide sequences.
• Pharmaceutical Research: Used in the R&D of peptide-based drugs, hormones, and diagnostic agents.
• Bioconjugation: Serves as a precursor for creating labeled peptides or peptide-drug conjugates.
• Biochemical Reagent: Employed in enzymatic studies and as a substrate analog in biochemical assays.
• Combinatorial Chemistry: Utilized in libraries for high-throughput screening of bioactive compounds.
• Academic Research: Fundamental building block in university and institutional labs for studying protein structure and function.

Basic Information

Product Name	H-Lys(Boc)-Obzl·Hcl
CAS No.	133170-57-7
Molecular Formula	C19H30N2O4·HCl
Molecular Weight	386.91 g/mol (Free base: 350.45)
Synonyms	Nε-Boc-L-lysine benzyl ester hydrochloride; Boc-Lys(Boc)-OBzl hydrochloride; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)hexanoic acid benzyl ester hydrochloride; Fmoc-Lys(Boc)-OH benzyl ester hydrochloride; Boc-Lys-OBzl·HCl; Nα-Boc-Nε-Cbz-L-lysine benzyl ester (common misnomer); Protected L-Lysine benzyl ester HCl salt
EINECS	Contact for details

Quality Control

Our H-Lys(Boc)-Obzl·Hcl is manufactured under strict quality systems to ensure batch-to-batch consistency suitable for research and cGMP starting material applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant ICH guidelines for stability and impurity characterization. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to maintain stability and prevent hydrolysis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Specific Rotation	[α]D20: Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Single Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.