Description

(S)-Methyl 2-(Diphenylmethyleneamino)-3-Hydroxypropanoate CAS NO 133157-01-4 is a high-purity chiral intermediate characterized by its diphenylmethyleneamino and hydroxypropanoate functional groups. This compound is of significant value in asymmetric synthesis, serving as a critical building block for the production of complex, optically active pharmaceuticals and fine chemicals. It is primarily required by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for developing novel active ingredients and chiral catalysts.

Application

• Key chiral intermediate in the synthesis of pharmaceutical active ingredients (APIs), particularly for β-blockers and other cardiovascular drugs.
• Building block for asymmetric catalysts and ligands used in enantioselective transformations.
• Precursor in the research and development of agrochemicals, such as herbicides and fungicides with specific stereochemistry.
• Starting material for the synthesis of unnatural amino acids and peptide mimetics.
• Intermediate in the production of specialty fine chemicals and advanced organic materials.
• Used in academic and industrial R&D for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	(S)-Methyl 2-(Diphenylmethyleneamino)-3-Hydroxypropanoate
CAS No.	133157-01-4
Molecular Formula	C17H17NO3
Molecular Weight	283.32 g/mol
Synonyms	(S)-Methyl 2-((Diphenylmethylene)amino)-3-hydroxypropanoate; Methyl (2S)-2-[(Diphenylmethylidene)amino]-3-hydroxypropanoate; (S)-Methyl 2-[(Diphenylmethylene)amino]-3-hydroxypropionate; L-Serine, N-(diphenylmethylene)-, methyl ester; (S)-Methyl N-(diphenylmethylene)serinate; (S)-Methyl 2-(benzhydrylideneamino)-3-hydroxypropanoate; (S)-Methyl O-benzhydrylideneserinate
EINECS	Contact for details

Quality Control

Our (S)-Methyl 2-(Diphenylmethyleneamino)-3-Hydroxypropanoate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting research and pharmaceutical intermediate standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.