Description

8-Bromo-Chroman-3-Ylamine Hydrochloride is a high-purity, pharmaceutically relevant organic building block. This compound is valued for its role as a key chiral intermediate in the synthesis of complex bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel pharmacophores containing the chroman scaffold.
• Process Chemistry Development: Employed in scaling up synthetic routes for Active Pharmaceutical Ingredients (APIs) during pilot plant and manufacturing stages.
• Chemical Biology Probes: Acts as a precursor for labeled compounds used in biochemical assays and target identification studies.
• Academic Research: Utilized in universities and research institutes for methodological development in asymmetric synthesis and heterocyclic chemistry.

Basic Information

Product Name	8-Bromo-Chroman-3-Ylamine Hydrochloride
CAS No.	133118-82-8
Molecular Formula	C9H11BrClNO
Molecular Weight	264.55 g/mol
Synonyms	3-Amino-8-bromochroman hydrochloride; 8-Bromo-3,4-dihydro-2H-1-benzopyran-3-amine hydrochloride; (3-Amino-8-bromo-3,4-dihydro-2H-chromen) hydrochloride; 8-Bromo-2,3-dihydro-4H-1-benzopyran-3-amine hydrochloride; 8-Bromochroman-3-amine HCl; 8-Bromo-3-chromanamine hydrochloride; 3-Amino-8-bromochroman HCl
EINECS	Contact for details

Quality Control

Our 8-Bromo-Chroman-3-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent high quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.