Description

8-Bromo-3-Chromanone is a versatile brominated heterocyclic ketone building block of significant interest in advanced organic synthesis. Its value lies in its unique molecular scaffold, which serves as a key precursor for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial synthon for the development of novel central nervous system (CNS) agents, enzyme inhibitors, and other bioactive molecules.
• Agrochemical Research: Used in the synthesis of new herbicides, fungicides, and plant growth regulators, leveraging its bromine atom for further functionalization.
• Material Science Precursor: Serves as a building block for organic semiconductors, liquid crystals, and advanced polymers due to its rigid chromanone core.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological pathways and protein interactions.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and ring-forming transformations.
• Fine Chemical Synthesis: Used in the multi-step synthesis of flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	8-Bromo-3-Chromanone
CAS No.	133118-80-6
Molecular Formula	C9H7BrO2
Molecular Weight	227.06 g/mol
Synonyms	8-Bromochroman-3-one; 3-Chromanone, 8-bromo-; 8-Bromo-3,4-dihydro-2H-1-benzopyran-3-one; 8-Bromo-2,3-dihydro-4H-chromen-4-one; 8-Bromochromanone; 8-Bromo-4-chromanone
EINECS	Contact for details

Quality Control

Our 8-Bromo-3-Chromanone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.