Description

4H-(1,2,4)Triazolo(4,3-A)(1,5)Benzodiazepin-5-Amine, N,n-Diethyl-1-Phe Nyl- is a high-purity, specialized heterocyclic compound belonging to the triazolobenzodiazepine class, serving as a critical advanced intermediate in modern pharmaceutical synthesis. Its value lies in enabling the development of novel therapeutic agents, particularly for central nervous system (CNS) targets, due to its unique fused-ring structure. This product is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs) and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel benzodiazepine and triazole-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and the discovery of new drug candidates targeting neurological and psychiatric disorders.
• Preclinical Development: Serves as a reference standard or starting material for producing compounds for pharmacological and toxicological studies.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, complex molecules.
• Chemical Biology Probes: Utilized in the development of molecular probes to study receptor binding and enzyme function in biological systems.

Basic Information

Product Name	4H-(1,2,4)Triazolo(4,3-A)(1,5)Benzodiazepin-5-Amine, N,n-Diethyl-1-Phe Nyl-
CAS No.	133118-25-9
Molecular Formula	C20H22N6
Molecular Weight	346.43 g/mol
Synonyms	N,N-Diethyl-1-phenyl-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-5-amine; 1-Phenyl-N,N-diethyl-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-5-amine; 133118-25-9; Triazolobenzodiazepine derivative; 5-Amino-1-phenyl-N,N-diethyl-4H-triazolo[4,3-a][1,5]benzodiazepine
EINECS	Contact for details

Quality Control

Our 4H-(1,2,4)Triazolo(4,3-A)(1,5)Benzodiazepin-5-Amine, N,n-Diethyl-1-Phe Nyl- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.