Description

tert-Butyl 1-Amino-2-Methyl-1-Thioxopropan-2-Ylcarbamate is a specialized organic compound featuring a protected amino and thioxo functional group on a propanamide backbone. This chemical serves as a versatile and critical building block (synthon) in advanced organic synthesis, particularly for the construction of complex molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of peptidomimetics, protease inhibitors, and other bioactive molecules.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific thioamide functionalities.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs for the production of client-specific, high-value chemical entities.
• Academic & Industrial Research: Serves as a reagent in methodological development and the exploration of new chemical spaces in medicinal chemistry.
• Peptide Chemistry: Functions as a protected cysteine analog or a scaffold for introducing thioamide bonds into peptide chains.

Basic Information

Product Name	tert-Butyl 1-Amino-2-Methyl-1-Thioxopropan-2-Ylcarbamate
CAS No.	133117-98-3
Molecular Formula	C9H18N2O2S
Molecular Weight	218.32 g/mol
Synonyms	2-[(tert-Butoxycarbonyl)amino]-2-methylpropanethioamide; N-(tert-Butoxycarbonyl)-2-amino-2-methylpropanethioamide; Boc-Aminoisobutyric thioamide; 1-Amino-2-methyl-1-thioxopropan-2-ylcarbamic acid tert-butyl ester; tert-Butyl (1-amino-2-methyl-1-thioxopropan-2-yl)carbamate; 2-(Boc-amino)-2-methylpropionthioamide
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-Amino-2-Methyl-1-Thioxopropan-2-Ylcarbamate is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent composition. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.