Description

Telmisartan Bromo Ethyl Ester CAS NO 133085-87-7 is a key pharmaceutical intermediate in the synthesis of Telmisartan, a widely prescribed angiotensin II receptor blocker (ARB) used to treat hypertension. This high-purity intermediate is critical for ensuring the final API's efficacy, safety, and regulatory compliance. It is primarily required by pharmaceutical manufacturers, R&D laboratories, and fine chemical suppliers engaged in the production of cardiovascular medications.

Application

• Primary Intermediate in the commercial synthesis of the active pharmaceutical ingredient (API) Telmisartan.
• Research & Development for novel ARB derivatives and related cardiovascular drug candidates.
• Process Chemistry optimization and scale-up studies within pharmaceutical manufacturing.
• Reference Standard for analytical method development and quality control in API production.
• Contract Manufacturing for companies specializing in high-value pharmaceutical intermediates.

Basic Information

Product Name	Telmisartan Bromo Ethyl Ester
CAS No.	133085-87-7
Molecular Formula	C33H30BrN4O2
Molecular Weight	609.53 g/mol
Synonyms	4'-[(1,7'-Dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carboxylic Acid, 2-Bromoethyl Ester; 2-Bromoethyl 4'-[(1,7'-Dimethyl-2'-propyl-1H,3'H-2,6'-bibenzimidazol-1'-yl)methyl]biphenyl-2-carboxylate; Telmisartan 2-Bromoethyl Ester; Telmisartan Bromoethyl Ester; Telmisartan Ethyl Bromide Ester; BIBR-277 Bromoethyl Ester; Intermediate of Telmisartan
EINECS	Contact for details

Quality Control

Our Telmisartan Bromo Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, supporting compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.