Description

(1S)-1-(2-Chlorophenyl)Ethane-1,2-Diol CAS NO 133082-13-0 is a high-purity chiral diol intermediate of significant importance in asymmetric synthesis. Its defined stereochemistry makes it a valuable building block for constructing complex molecules with specific three-dimensional orientations. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure drugs, particularly those targeting neurological or cardiovascular systems.
• Asymmetric Catalyst Ligand Precursor: Used to develop and synthesize novel chiral ligands for transition metal catalysis.
• Fine Chemical Synthesis: Serves as a building block for agrochemicals, specialty polymers, and liquid crystals.
• Academic & Process Research: Employed in methodological development and scale-up studies for stereoselective reactions.
• Reference Standard: Used as a high-purity standard for analytical method development and quality control in chiral separations.

Basic Information

Product Name	(1S)-1-(2-Chlorophenyl)Ethane-1,2-Diol
CAS No.	133082-13-0
Molecular Formula	C8H9ClO2
Molecular Weight	172.61 g/mol
Synonyms	(S)-1-(2-Chlorophenyl)-1,2-ethanediol; (1S)-1-(2-Chlorophenyl)-1,2-ethanediol; (S)-2-Chloromandelic Alcohol; (S)-(-)-2-Chloromandelic Alcohol; (S)-1-(2-Chlorophenyl)ethane-1,2-diol; (S)-2-Chloro-1-phenylethane-1,2-diol; (1S)-1-(2-Chlorophenyl)ethane-1,2-diol; L-1-(2-Chlorophenyl)Ethane-1,2-Diol
EINECS	Contact for details

Quality Control

Our (1S)-1-(2-Chlorophenyl)Ethane-1,2-Diol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay and impurity profiling by HPLC, to ensure it meets exacting research and pharmaceutical-grade standards. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.