Description

6-Oxabicyclo[3.1.0]Hexane-2-Carboxamide,2,4-Dihydroxy-,(1R,2S,4R,5R)-(9Ci) is a high-purity, stereochemically defined bicyclic compound that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its unique oxabicyclo[3.1.0]hexane scaffold, featuring multiple functional groups, makes it invaluable for constructing complex molecular architectures with precise stereochemical control. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in antiviral, anticancer, and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where the specific spatial orientation of the molecule is crucial for biological activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts used in enantioselective transformations.
• Material Science Research: Investigated as a monomer or cross-linking agent for producing polymers with unique thermal or mechanical properties due to its strained ring system.
• Academic & Process Chemistry: Employed in methodological studies and scale-up process optimization for complex multi-step syntheses requiring high stereochemical fidelity.

Basic Information

Product Name	6-Oxabicyclo[3.1.0]Hexane-2-Carboxamide,2,4-Dihydroxy-,(1R,2S,4R,5R)-(9Ci)
CAS No.	133071-12-2
Molecular Formula	C7H9NO4
Molecular Weight	171.15 g/mol
Synonyms	(1R,2S,4R,5R)-2,4-Dihydroxy-6-oxabicyclo[3.1.0]hexane-2-carboxamide; (1R,2S,4R,5R)-2,4-Dihydroxy-6-oxabicyclo[3.1.0]hexane-2-carboxylic acid amide; 2,4-Dihydroxy-6-oxabicyclo[3.1.0]hexane-2-carboxamide, (1R,2S,4R,5R)-; (-)-2,4-Dihydroxy-6-oxabicyclo[3.1.0]hexane-2-carboxamide; Chiral Oxabicyclohexane Carboxamide; Bicyclic Hydroxy Carboxamide Intermediate
EINECS	Contact for details

Quality Control

Our 6-Oxabicyclo[3.1.0]Hexane-2-Carboxamide,2,4-Dihydroxy-,(1R,2S,4R,5R)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture uptake and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.