Description

Paclitaxel Side Chain No 1 (CAS NO 133066-61-2) is a key chiral intermediate in the semi-synthetic production of the potent anticancer drug Paclitaxel. Its precise stereochemistry and high purity are critical for ensuring the efficacy and safety of the final active pharmaceutical ingredient. This compound is essential for pharmaceutical manufacturers and research institutions engaged in oncology drug development and advanced synthetic chemistry.

Application

• Primary Intermediate for the semi-synthesis of Paclitaxel (Taxol®) and related taxane analogs.
• Pharmaceutical Research & Development for creating novel taxane-based chemotherapeutic agents.
• Process Chemistry in scaling up the commercial production of Paclitaxel API.
• Reference Standard for quality control and analytical method development in pharmaceutical labs.
• Academic Research in medicinal chemistry and organic synthesis studies.

Basic Information

Product Name	Paclitaxel Side Chain No 1
CAS No.	133066-61-2
Molecular Formula	C13H17NO5
Molecular Weight	267.28 g/mol
Synonyms	(2R,3S)-3-Benzamido-2-hydroxy-3-phenylpropanoic Acid; N-Benzoyl-3-phenylisoserine; Baccatin III Side Chain; C-13 Paclitaxel Side Chain; 3-Phenylisoserine Derivative; Taxol Side Chain Precursor; (αR,βS)-β-(Benzoylamino)-α-hydroxybenzenepropanoic Acid
EINECS	Contact for details

Quality Control

Our Paclitaxel Side Chain No 1 is manufactured under strict quality management systems suitable for pharmaceutical intermediate applications. Each batch undergoes comprehensive analytical testing, including chiral purity and impurity profile analysis by HPLC, to ensure it meets exacting standards. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.5%
Chiral Purity (HPLC)	≥ 99.0%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.