Description

(Naphthyl)Hydroxy-Naftopidil is a high-purity pharmaceutical intermediate and research chemical with the CAS number 133024-36-9. This compound is of significant interest for its role in the synthesis and development of novel therapeutic agents, particularly in urology and cardiovascular research. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of Naftopidil and related α-1 adrenergic receptor antagonists.
• Medicinal Chemistry Research: Used as a reference standard or precursor in the development of new drug candidates targeting benign prostatic hyperplasia (BPH).
• Biochemical Studies: Serves as a tool compound for investigating receptor-ligand interactions and pharmacological mechanisms.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing of specialized active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for pharmacological and synthetic chemistry studies.
• Quality Control Standard: Acts as a high-purity analytical reference material for HPLC and other chromatographic methods.

Basic Information

Product Name	(Naphthyl)Hydroxy-Naftopidil
CAS No.	133024-36-9
Molecular Formula	C₂₄H₂₈N₂O₃
Molecular Weight	392.49 g/mol
Synonyms	1-[4-(2-Methoxyphenyl)piperazin-1-yl]-3-(naphthalen-1-yloxy)propan-2-ol; 1-(4-(2-Methoxyphenyl)piperazin-1-yl)-3-(naphthalen-1-yloxy)propan-2-ol; Naftopidil Impurity; Naftopidil Related Compound; Hydroxy Naftopidil; Naftopidil Intermediate; FL-113 Metabolite
EINECS	Contact for details

Quality Control

Our (Naphthyl)Hydroxy-Naftopidil is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and pharmaceutical intermediate standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.