Description

3-(3-Trifluoromethylphenoxy)Azetidine Oxalate is a high-purity, specialized organic salt used as a critical pharmaceutical intermediate. Its value lies in its role as a key building block for synthesizing advanced active pharmaceutical ingredients (APIs) and other fine chemicals. This compound is essential for research and development laboratories, process chemists, and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors seeking reliable, high-quality intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the trifluoromethyl group for enhanced biological activity and stability.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of monomers or additives for specialty polymers with unique fluorinated properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis and Scale-up: Supplied for contract research organizations (CROs) and contract development and manufacturing organizations (CDMOs) for custom synthesis projects from gram to kilogram scale.

Basic Information

Product Name	3-(3-Trifluoromethylphenoxy)Azetidine Oxalate
CAS No.	132924-64-2
Molecular Formula	C12H12F3NO5
Molecular Weight	307.23 g/mol
Synonyms	3-[3-(Trifluoromethyl)phenoxy]azetidine oxalate; 3-(3-Trifluoromethylphenoxy)azetidine hydrogen oxalate; Azetidine, 3-[3-(trifluoromethyl)phenoxy]-, ethanedioate (1:1); 3-(α,α,α-Trifluoro-m-tolyloxy)azetidine oxalate; 3-(m-Trifluoromethylphenoxy)azetidine oxalic acid salt
EINECS	Contact for details

Quality Control

Every batch of 3-(3-Trifluoromethylphenoxy)Azetidine Oxalate is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency, meeting the stringent requirements for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.