Description

1-(Diphenylmethyl)-3-(3-Fluorophenoxy)-Azetidine Oxalate is a high-purity, non-racemic chiral building block and pharmaceutical intermediate. This compound is valued for its defined stereochemistry and structural complexity, which are critical for advanced organic synthesis and medicinal chemistry research. It is primarily needed by R&D laboratories and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Research: Used as a precursor in the synthesis of novel pesticides and herbicides, leveraging the fluorophenoxy moiety.
• Asymmetric Synthesis: Serves as a sophisticated building block in catalytic asymmetric reactions to construct complex molecular architectures.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization programs due to its unique azetidine and diphenylmethyl groups.
• Process Chemistry Development: Used for scaling up synthetic routes and developing robust manufacturing processes for active pharmaceutical ingredients (APIs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in regulatory filings.

Basic Information

Product Name	1-(Diphenylmethyl)-3-(3-Fluorophenoxy)-Azetidine Oxalate
CAS No.	132924-42-6
Molecular Formula	C24H22FNO5
Molecular Weight	423.44 g/mol
Synonyms	1-(Benzhydryl)-3-(3-fluorophenoxy)azetidine oxalate; 3-(3-Fluorophenoxy)-1-(diphenylmethyl)azetidine oxalate; 1-(Diphenylmethyl)-3-(3-fluorophenoxy)azetidine ethanedioate; Azetidine, 1-(diphenylmethyl)-3-(3-fluorophenoxy)-, oxalate (1:1); (R/S)-1-(Diphenylmethyl)-3-(3-fluorophenoxy)azetidine oxalate salt; 132924-42-6; 1-(α-Phenylbenzyl)-3-(m-fluorophenoxy)azetidine oxalate
EINECS	Contact for details

Quality Control

Our 1-(Diphenylmethyl)-3-(3-Fluorophenoxy)-Azetidine Oxalate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination, to ensure it meets the stringent requirements for advanced research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.