Description

5-Hydroxy-7,2'',3'',4'',5''-Pentamethoxyflavone is a polymethoxylated flavonoid, a specialized subclass of natural compounds known for their distinct biological activities. This high-purity reference standard is critical for research and development in life sciences, where precise chemical identity and purity are non-negotiable. It is primarily sought by pharmaceutical researchers, analytical laboratories, and manufacturers of nutraceutical ingredients for use in bioactivity studies, method validation, and as a key phytochemical marker.

Application

• Pharmaceutical Reference Standard: Used for the identification, assay, and purity testing of flavonoid-based drug candidates and herbal extracts in compliance with pharmacopeial methods (e.g., USP, EP).
• Biochemical Research: Serves as a key intermediate or active compound in studies investigating anti-inflammatory, antioxidant, and neuroprotective mechanisms.
• Natural Product Analysis: Acts as a critical calibration standard in HPLC, LC-MS, and NMR for the quantification of polymethoxylated flavonoids in complex botanical matrices.
• Nutraceutical Development: Employed in the formulation and standardization of high-value dietary supplements where specific flavonoid content is a claimed benefit.
• Academic Research: Utilized in universities and research institutes for synthetic chemistry, metabolic pathway studies, and structure-activity relationship (SAR) investigations.

Basic Information

Product Name	5-Hydroxy-7,2'',3'',4'',5''-Pentamethoxyflavone
CAS No.	132923-24-1
Molecular Formula	C₂₀H₂₀O₈
Molecular Weight	388.37 g/mol
Synonyms	5-Hydroxy-7,2',3',4',5'-pentamethoxyflavone; 5-Hydroxy-7,2',3',4',5'-pentamethoxyflavanone (common misnomer); PMF derivative; Pentamethoxyflavone; 7,2',3',4',5'-Pentamethoxy-5-hydroxyflavone; NSC 407303; Flavone, 5-hydroxy-7,2',3',4',5'-pentamethoxy-
EINECS	Contact for details

Quality Control

Every batch of our 5-Hydroxy-7,2'',3'',4'',5''-Pentamethoxyflavone is manufactured and controlled under a strict quality management system. We provide comprehensive analytical documentation to support your regulatory and research requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot. Our standard material is suitable for use as an analytical reference standard, with specifications designed to meet the needs of research and quality control laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.