Description

n-Boc-Dl-Pipecolic Acid Methyl Ester is a protected amino acid derivative that serves as a crucial chiral building block in organic synthesis. This compound is valued for its role in introducing the pipecolic acid scaffold, a key structural motif in bioactive molecules. It is primarily utilized by pharmaceutical and biotechnology research organizations for the development of novel therapeutic agents, including protease inhibitors and other pharmacologically active compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of drug candidates targeting various diseases.
• Peptidomimetics Research: Used to incorporate constrained, non-proteinogenic amino acid structures into peptide analogs to enhance stability and bioavailability.
• Protease Inhibitor Development: Serves as a core building block in the creation of inhibitors for enzymes like dipeptidyl peptidase IV (DPP-4) and others.
• Chemical Biology Probes: Employed in the synthesis of labeled or tagged compounds for studying biological pathways and target engagement.
• Agrochemical Synthesis: Potential intermediate in the development of advanced pesticides and herbicides with specific chiral activity.
• Academic & Contract Research: Essential reagent for methodological development in asymmetric synthesis and medicinal chemistry projects.

Basic Information

Product Name	n-Boc-Dl-Pipecolic Acid Methyl Ester
CAS No.	132910-79-3
Molecular Formula	C12H21NO4
Molecular Weight	243.30 g/mol
Synonyms	1-Boc-3,4-dehydropipecolic acid methyl ester; Methyl 1-(tert-butoxycarbonyl)-3,4-dehydropipecolate; tert-Butyl 2-methoxy-2-oxo-3,4-dehydro-1-piperidinecarboxylate; DL-1-Boc-3,4-dehydropipecolic acid methyl ester; (RS)-1-Boc-3,4-dehydropipecolic acid methyl ester; 3,4-Dehydro-1-N-Boc-pipecolic acid methyl ester; Methyl 1-N-Boc-3,4-dehydropipecolate
EINECS	Contact for details

Quality Control

Our n-Boc-Dl-Pipecolic Acid Methyl Ester is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	DL-mixture (Racemic)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.