Description

6-Amino-4-(2,5-Dimethoxyphenyl)-3-Methyl-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyranopyrazole class of heterocyclic compounds. This compound is valued for its complex molecular architecture, which serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used as a core scaffold in the development of new-generation pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Chemical Biology & Medicinal Chemistry: Serves as a versatile building block for constructing compound libraries used in high-throughput screening (HTS) and structure-activity relationship (SAR) studies.
• Organic Synthesis Research: Employed in academic and industrial R&D for methodological studies involving multicomponent reactions (MCRs) and the construction of complex fused heterocycles.
• Dye & Pigment Intermediate: Potential use in the synthesis of specialized organic colorants and functional materials due to its conjugated system and electron-donating/accepting groups.

Basic Information

Product Name	6-Amino-4-(2,5-Dimethoxyphenyl)-3-Methyl-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile
CAS No.	132814-01-8
Molecular Formula	C₁₆H₁₆N₄O₃
Molecular Weight	312.33 g/mol
Synonyms	6-Amino-3-methyl-4-(2,5-dimethoxyphenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile; 4-(2,5-Dimethoxyphenyl)-6-amino-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile; Pyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-4-(2,5-dimethoxyphenyl)-3-methyl-1,4-dihydro-; Fused Pyranopyrazole Derivative; DHPP Carbonitrile Intermediate
EINECS	Contact for details

Quality Control

Every batch of 6-Amino-4-(2,5-Dimethoxyphenyl)-3-Methyl-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency that meet the exacting standards of pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.