Description

4-(4-Fluorophenyl)-5,6,7,8,9,10-Hexahydrocycloocta[B]Pyridin-2(1H)-One is a high-value, complex heterocyclic compound featuring a fused cyclooctane and pyridinone structure with a fluorophenyl substituent. This molecular architecture makes it a critical advanced pharmaceutical intermediate for the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and oncology research. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing next-generation small molecule drugs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Preclinical Development: Used to produce batches of active pharmaceutical ingredients (APIs) for pharmacological and toxicological evaluation.
• Chemical Biology Probe: Serves as a precursor for developing tool compounds to study specific biological pathways and protein functions.
• Organic Synthesis Reference Standard: High-purity material used as a benchmark in analytical method development and validation.

Basic Information

Item	Details
Product Name	4-(4-Fluorophenyl)-5,6,7,8,9,10-Hexahydrocycloocta[B]Pyridin-2(1H)-One
CAS No.	132812-72-7
Molecular Formula	C19H20FNO
Molecular Weight	297.37 g/mol
Synonyms	4-(4-Fluorophenyl)-1,2,3,5,6,7,8,9-octahydrocycloocta[b]pyridin-2-one; 4-(p-Fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridin-2(1H)-one; 132812-72-7; Cycloocta[b]pyridin-2(1H)-one, 4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydro-; Fluorophenyl Hexahydrocycloocta[B]Pyridinone
EINECS	Contact for details

Quality Control

Every batch of our 4-(4-Fluorophenyl)-5,6,7,8,9,10-Hexahydrocycloocta[B]Pyridin-2(1H)-One is manufactured under strict quality management systems and undergoes comprehensive analytical characterization. We provide full traceability and Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, ensuring compliance with the stringent requirements of pharmaceutical development. Specifications are aligned with ICH guidelines for impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.