Description

n-[9-(2-Fluoro-2,3-Dideoxy-β-D-Threo-Pentofuranosyl)-9H-Purine-6-Yl]Benzamide CAS NO 132722-93-1 is a high-purity nucleoside analogue derivative, a critical building block in advanced pharmaceutical research and development. This compound matters for its role as a key intermediate in the synthesis of novel antiviral and anticancer therapeutics, enabling the exploration of targeted mechanisms of action. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing next-generation nucleotide-based drugs.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of experimental antiviral agents, particularly those targeting viral polymerases.
• Anticancer Drug Research: Used in the development and screening of novel chemotherapeutic compounds that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Research: Acts as a modified nucleoside probe in enzymatic studies and metabolic pathway analysis.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of nucleotide analogues.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Process Development: Supports scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs) in pilot plants.

Basic Information

Product Name	n-[9-(2-Fluoro-2,3-Dideoxy-β-D-Threo-Pentofuranosyl)-9H-Purine-6-Yl]Benzamide
CAS No.	132722-93-1
Molecular Formula	C₁₇H₁₆FN₅O₄
Molecular Weight	373.34 g/mol
Synonyms	2'-Fluoro-2',3'-dideoxy-N6-benzoyladenosine; 9-(2-Fluoro-2,3-dideoxy-β-D-threo-pentofuranosyl)-N-benzoyladenine; 2'-F-ddA Benzamide; N-Benzoyl-2'-fluoro-2',3'-dideoxyadenosine; 2'-F-2',3'-ddA-N6-benzamide; 132722-93-1; Adenosine, 2'-fluoro-2',3'-dideoxy-, 6-N-benzoyl-; 6-Benzamido-9-(2-fluoro-2,3-dideoxy-β-D-threo-pentofuranosyl)-9H-purine
EINECS	Contact for details

Quality Control

Our n-[9-(2-Fluoro-2,3-Dideoxy-β-D-Threo-Pentofuranosyl)-9H-Purine-6-Yl]Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.