Description

9-(2,3-Dideoxy-2-Fluoro-β-D-Threo-Pentofuranosyl)-2-Methyl-9H-Purine-6-Amine is a high-purity nucleoside analog, a key building block in advanced pharmaceutical research and development. This compound is critical for the synthesis of novel antiviral and anticancer agents, offering researchers a precise tool for probing biological mechanisms and developing targeted therapies. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of nucleoside-based antiviral drugs, particularly for research into novel therapeutic agents.
• Medicinal Chemistry Research: Serves as a sophisticated building block for structure-activity relationship (SAR) studies and the development of targeted small-molecule inhibitors.
• Antiviral Drug Development: Used in the research and development of potential treatments for viral infections, leveraging its modified nucleoside structure.
• Oncology Research: Investigated as a component in the design of prodrugs and chemotherapeutic agents that target cellular replication pathways.
• Biochemical Tool Compound: Employed in enzymatic studies and as a probe to understand nucleoside metabolism and related biological processes.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis (HPLC, LC-MS).

Basic Information

Product Name	9-(2,3-Dideoxy-2-Fluoro-β-D-Threo-Pentofuranosyl)-2-Methyl-9H-Purine-6-Amine
CAS No.	132722-91-9
Molecular Formula	C11H14FN5O2
Molecular Weight	267.26 g/mol
Synonyms	2-Methyl-2'-fluoro-2',3'-dideoxyadenosine; 2'-F-2',3'-ddA; 2'-Fluoro-2',3'-dideoxyadenosine; 9H-Purine-6-amine, 9-(2,3-dideoxy-2-fluoro-β-D-threo-pentofuranosyl)-2-methyl-; 2'-F-ddA; 2-Methyl-2'-fluoro-2',3'-dideoxyadenosine (2'-F-ddA); 2'-Fluoro-2',3'-dideoxy-2-methyladenosine
EINECS	Contact for details

Quality Control

Every batch of 9-(2,3-Dideoxy-2-Fluoro-β-D-Threo-Pentofuranosyl)-2-Methyl-9H-Purine-6-Amine is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) confirming identity, purity (typically ≥95% by HPLC), and impurity profile is supplied with each shipment to guarantee reproducible results in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 5.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.