Description

9-(2',3'-Dideoxy-2'-Fluoroarabinofuranosyl)Purine is a specialized nucleoside analog, a key building block in medicinal chemistry and pharmaceutical research. Its unique fluorinated sugar moiety makes it a valuable intermediate for developing novel antiviral and anticancer therapeutics. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical synthesis sectors seeking to innovate in nucleoside-based drug discovery.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of experimental antiviral and anticancer nucleoside analogs.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Biochemical Probes: Serves as a tool compound for studying enzyme mechanisms, particularly those involving nucleoside kinases and polymerases.
• Antiviral Drug Development: A key starting material for synthesizing potential therapeutics targeting viral replication.
• Academic & Institutional Research: Utilized in university and government labs for fundamental research in nucleic acid chemistry and biology.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development pipelines.

Basic Information

Product Name	9-(2',3'-Dideoxy-2'-Fluoroarabinofuranosyl)Purine
CAS No.	132722-90-8
Molecular Formula	C₁₀H₁₂FN₅O₂
Molecular Weight	253.23 g/mol
Synonyms	2'-Fluoro-2',3'-dideoxyarabinofuranosylpurine; 9-[(2R,3S,4S)-3-Fluoro-4-(hydroxymethyl)oxolan-2-yl]purine; 2'-F-ara-ddPurine; 2'-Fluoro-2',3'-dideoxyarabinofuranosyladenine (common misnomer); 2'-F-ddAra-Purine; 132722-90-8; 9-(2',3'-Dideoxy-2'-fluoro-β-D-arabinofuranosyl)purine
EINECS	Contact for details

Quality Control

Our 9-(2',3'-Dideoxy-2'-Fluoroarabinofuranosyl)Purine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.