Description

(R)-3-(Boc-Amino)-2-Methylpropionic Acid is a high-purity, non-natural amino acid derivative featuring a chiral center and a tert-butoxycarbonyl (Boc) protecting group. This compound is a critical chiral building block for the synthesis of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing peptide-based therapeutics and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel APIs, particularly for peptide and peptidomimetic drugs.
• Peptide Synthesis: Serves as a protected amino acid component in solid-phase and solution-phase peptide synthesis (SPPS).
• Protease Inhibitor Development: Used in the research and production of inhibitors targeting specific enzymes.
• Chemical Biology & Research: Employed as a tool compound for studying biological pathways and protein-protein interactions.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or starting material in stereoselective chemical reactions.
• Fine Chemical Production: A building block for creating complex, high-value specialty chemicals with specific stereochemistry.

Basic Information

Product Name	(R)-3-(Boc-Amino)-2-Methylpropionic Acid
CAS No.	132696-45-8
Molecular Formula	C10H19NO4
Molecular Weight	217.26 g/mol
Synonyms	(R)-3-[(tert-Butoxycarbonyl)amino]-2-methylpropanoic acid; (R)-2-Methyl-3-[(tert-butoxycarbonyl)amino]propionic acid; Boc-D-β-homoalanine; (R)-Boc-β-homoalanine; (R)-N-Boc-2-methyl-β-alanine; (R)-3-(tert-Butoxycarbonylamino)-2-methylpropionic acid; (R)-N-(tert-Butoxycarbonyl)-2-methyl-β-alanine; D-Boc-β-homoalanine
EINECS	Contact for details

Quality Control

Our (R)-3-(Boc-Amino)-2-Methylpropionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.