Description

[4-(2-Boc-Amino-Ethyl)-Phenyl]-Acetic Acid is a high-purity, protected amino acid derivative widely used as a critical building block in organic synthesis. This compound is essential for the controlled introduction of functional groups, enabling the development of complex molecules with high specificity. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and peptide-based therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis for the controlled incorporation of specific amino acid sequences.
• Linker Molecule: Serves as a versatile spacer or linker in the construction of bioconjugates, antibody-drug conjugates (ADCs), and targeted drug delivery systems.
• Chemical Biology Research: Employed in the synthesis of molecular probes, enzyme inhibitors, and other tools for biochemical and pharmacological studies.
• Custom Synthesis: A foundational starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals.

Basic Information

Product Name	[4-(2-Boc-Amino-Ethyl)-Phenyl]-Acetic Acid
CAS No.	132691-14-6
Molecular Formula	C₁₅H₂₁NO₄
Molecular Weight	279.33 g/mol
Synonyms	2-[4-(2-[(tert-Butoxycarbonyl)amino]ethyl)phenyl]acetic acid; N-Boc-2-(4-aminomethylphenyl)acetic acid; 4-(2-(tert-Butoxycarbonylamino)ethyl)phenylacetic acid; (4-{2-[(tert-Butoxycarbonyl)amino]ethyl}phenyl)acetic acid; Boc-Tyr(2-aminoethyl)-OH; N-Boc-4-(2-aminoethyl)phenylacetic acid; tert-Butyl N-[2-(4-carboxymethylphenyl)ethyl]carbamate
EINECS	Contact for details

Quality Control

Our [4-(2-Boc-Amino-Ethyl)-Phenyl]-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.