Description

4-(2-Boc-Aminoethyl)Benzoic Acid is a high-purity, protected amino acid derivative that serves as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular architecture, particularly in the development of complex active pharmaceutical ingredients (APIs) and peptide-based therapeutics. Its primary value lies in providing a versatile, orthogonally protected intermediate that enables the controlled elongation of molecular chains under standard coupling conditions. Key industries that rely on this material include pharmaceutical R&D, biotechnology, and fine chemical manufacturing for producing novel drug candidates and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex Active Pharmaceutical Ingredients (APIs), particularly for peptide-based drugs and small molecule therapeutics.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected amino acid derivative for introducing specific functional groups into peptide chains.
• Linker Chemistry: Serves as a versatile bifunctional linker molecule for conjugating pharmacophores, targeting moieties, or diagnostic agents in drug discovery.
• Protease Inhibitor Development: Employed in the research and production of protease inhibitors, where its structure mimics natural substrates.
• Chemical Biology Probes: Utilized to create labeled probes and tools for studying biological pathways and protein-protein interactions.
• Material Science: Acts as a monomer or functionalization agent in the synthesis of specialized polymers and advanced materials with tailored properties.

Basic Information

Product Name	4-(2-Boc-Aminoethyl)Benzoic Acid
CAS No.	132690-91-6
Molecular Formula	C16H23NO4
Molecular Weight	293.36 g/mol
Synonyms	4-[(2-{[(tert-Butoxy)carbonyl]amino}ethyl)]benzoic acid; 4-(2-((tert-Butoxycarbonyl)amino)ethyl)benzoic Acid; 4-(2-Boc-aminoethyl)benzoic Acid; Boc-NH-CH2-CH2-C6H4-COOH; 2-{[(tert-Butoxy)carbonyl]amino}ethyl]benzoic Acid; N-Boc-2-(4-carboxyphenyl)ethylamine; tert-Butyl N-[2-(4-carboxyphenyl)ethyl]carbamate; 4-(2-(tert-Butoxycarbonylamino)ethyl)benzoic Acid
EINECS	Contact for details

Quality Control

Our 4-(2-Boc-Aminoethyl)Benzoic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and cGMP applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, documenting critical parameters such as assay, chiral purity, and residual solvent levels. Our quality commitment aligns with ICH guidelines to support your regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH limits
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.