Description

(4R)-4-(Hydroxymethyl)-2-oxazolidinone is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic utility. Its value lies in its stereochemically defined structure, which is crucial for imparting specific biological activity in final active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development and production of novel therapeutics, particularly antibiotics and other chiral drugs. The product is supplied under stringent quality control to ensure batch-to-batch consistency for critical applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of oxazolidinone-class antibiotics, such as linezolid and tedizolid.
• Chiral Auxiliary: Used in asymmetric synthesis to induce stereoselectivity in the formation of new carbon-carbon or carbon-heteroatom bonds.
• Organic Synthesis Building Block: Employed in the construction of complex heterocyclic compounds and other bioactive molecules.
• Medicinal Chemistry Research: Serves as a core scaffold for designing and screening new drug candidates with improved efficacy and safety profiles.
• Process Chemistry: Utilized in the development and scale-up of efficient, cost-effective manufacturing routes for target molecules.

Basic Information

Product Name	(4R)-4-(Hydroxymethyl)-2-oxazolidinone
CAS No.	132682-23-6
Molecular Formula	C4H7NO3
Molecular Weight	117.10 g/mol
Synonyms	(R)-4-(Hydroxymethyl)-2-oxazolidinone; (4R)-4-(Hydroxymethyl)-1,3-oxazolidin-2-one; (R)-4-Hydroxymethyl-2-oxazolidinone; (R)-Oxazolidin-2-one, 4-(hydroxymethyl)-; (R)-4-Hydroxymethyloxazolidin-2-one; (R)-HMO; (R)-4-HMO; (R)-4-Hydroxymethyl-2-oxazolidone
EINECS	Contact for details

Quality Control

Our (4R)-4-(Hydroxymethyl)-2-oxazolidinone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity (HPLC), chemical purity (HPLC), and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.