Description

2,4-Dibromoestra-1,3,5(10),6-Tetraene-3,17-Diol Diacetate is a high-purity, brominated steroid derivative of significant interest in advanced pharmaceutical research and synthesis. This compound serves as a critical synthetic intermediate, enabling the development of novel therapeutic agents and facilitating structure-activity relationship (SAR) studies. It is primarily utilized by research institutions and pharmaceutical development companies focused on endocrinology, oncology, and the creation of specialized steroid-based molecules.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel steroid-based drug candidates and active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial laboratories for probing steroid receptor interactions and metabolic pathways.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development, validation, and quality control in steroid analysis.
• Precursor for Modified Steroids: The bromine atoms provide reactive sites for further functionalization, enabling the creation of libraries of structurally diverse steroid analogs.
• Biochemical Tool Compound: Employed in studies investigating the role of halogenated steroids in biological systems and enzyme inhibition.

Basic Information

Product Name	2,4-Dibromoestra-1,3,5(10),6-Tetraene-3,17-Diol Diacetate
CAS No.	132633-86-4
Molecular Formula	C22H24Br2O4
Molecular Weight	512.24 g/mol
Synonyms	2,4-Dibromoestra-1,3,5(10),6-tetraene-3,17β-diol diacetate; 2,4-Dibromo-3,17β-diacetoxyestra-1,3,5(10),6-tetraene; Estra-1,3,5(10),6-tetraene-3,17-diol, 2,4-dibromo-, diacetate; 2,4-Dibromoestra-1,3,5(10),6-tetraene-3,17-diol 3,17-diacetate; Brominated Estradiol Diacetate Derivative
EINECS	Contact for details

Quality Control

Our 2,4-Dibromoestra-1,3,5(10),6-Tetraene-3,17-Diol Diacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure full traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.