Description

3-Oxo-3-(2,4,5-Trifluoro-3,6-Dimethyl-Phenyl)-Propionic Acid Ethyl Ester is a high-value fluorinated aromatic keto ester building block, prized for its unique trifluoromethyl-substituted phenyl ring system. This compound is critical for introducing specific steric and electronic properties into target molecules, enabling advanced material and pharmaceutical development. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in fluorinated small molecule libraries.
• Agrochemical Synthesis: Used to construct advanced active ingredients for crop protection products, leveraging the stability and bioactivity of the trifluoromethyl group.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, or organic electronic materials requiring fluorinated aromatic components.
• Chemical Biology Probes: Employed in the synthesis of fluorinated probes and tags for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring complex, multi-fluorinated aromatic structures.
• Academic & Industrial R&D: Utilized in exploratory chemistry to study structure-activity relationships and develop new synthetic methodologies.

Basic Information

Product Name	3-Oxo-3-(2,4,5-Trifluoro-3,6-Dimethyl-Phenyl)-Propionic Acid Ethyl Ester
CAS No.	132630-88-7
Molecular Formula	C13H13F3O3
Molecular Weight	280.24 g/mol
Synonyms	Ethyl 3-(2,4,5-trifluoro-3,6-dimethylphenyl)-3-oxopropanoate; 3-(2,4,5-Trifluoro-3,6-dimethylphenyl)-3-oxopropanoic acid ethyl ester; 2,4,5-Trifluoro-3,6-dimethyl-β-oxobenzenepropanoic acid ethyl ester; Ethyl 3-oxo-3-(2,4,5-trifluoro-3,6-dimethylphenyl)propanoate; 3-Oxo-3-(2,4,5-trifluoro-3,6-dimethylphenyl)propionic acid ethyl ester; TFMP-Keto Ester; Trifluoromethyl Aromatic Keto Ester Intermediate
EINECS	Contact for details

Quality Control

Our 3-Oxo-3-(2,4,5-Trifluoro-3,6-Dimethyl-Phenyl)-Propionic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.