Description

Cyclopropanecarboxylic Acid, 2-(Aminomethyl)-, Methyl Ester, Hydrochloride, cis- (9Ci) is a high-purity, stereochemically defined chemical building block of significant interest in advanced organic synthesis. This compound matters as a key chiral intermediate, enabling the construction of complex molecules with precise three-dimensional architecture. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where its cis-configured cyclopropane and ester-protected amino acid functionalities are highly valuable.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where the cyclopropane moiety can enhance biological activity and stability.
• Peptidomimetics Research: Serves as a constrained, non-natural amino acid analog in the design of peptide-like molecules with improved metabolic stability and receptor selectivity.
• Chemical Biology Probes: Employed in the synthesis of specialized probes and ligands for studying enzyme mechanisms and protein interactions.
• Material Science: Potential monomer or precursor for specialty polymers with unique thermal or mechanical properties derived from the strained cyclopropane ring.
• Catalyst Ligand Development: Can be utilized to develop novel chiral ligands for asymmetric catalysis.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-(Aminomethyl)-, Methyl Ester, Hydrochloride, cis- (9Ci)
CAS No.	132592-83-7
Molecular Formula	C7H14ClNO2
Molecular Weight	179.64 g/mol
Synonyms	cis-2-(Aminomethyl)cyclopropanecarboxylic acid methyl ester hydrochloride; Methyl cis-2-(aminomethyl)cyclopropanecarboxylate hydrochloride; (1S,2R)-2-(Aminomethyl)cyclopropanecarboxylic acid methyl ester hydrochloride (if stereochemistry is specified); 2-(Aminomethyl)cyclopropanecarboxylic Acid Methyl Ester Hydrochloride (cis-); Cyclopropanecarboxylic acid, 2-(aminomethyl)-, methyl ester, hydrochloride, (1R,2S)-rel-; (1R,2S)-2-(Aminomethyl)cyclopropanecarboxylic acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2-(Aminomethyl)-, Methyl Ester, Hydrochloride, cis- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% cis-isomer
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.