Description

3-[(1R,3R)-3-{[(Dimethylcarbamoyl)Amino]Methyl}-3,5,5-Trimethylcyclohexyl]-1,1-Dimethylurea is a high-purity, stereochemically defined organic compound of significant interest in advanced chemical synthesis. This material serves as a critical chiral building block and intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for its unique structural framework and functional groups.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of advanced crop protection agents and pesticides due to its complex, functionalized cyclohexyl structure.
• Fine Chemical Synthesis: Serves as a sophisticated building block for creating complex molecules in custom synthesis and process development.
• Chemical Biology & Proteomics: Potential utility as a molecular probe or linker in biochemical research and drug discovery platforms.
• Material Science Research: Investigated for incorporation into specialty polymers or advanced materials requiring specific stereochemistry.

Basic Information

Product Name	3-[(1R,3R)-3-{[(Dimethylcarbamoyl)Amino]Methyl}-3,5,5-Trimethylcyclohexyl]-1,1-Dimethylurea
CAS No.	132580-72-4
Molecular Formula	C16H32N4O2
Molecular Weight	312.45 g/mol
Synonyms	1,1-Dimethyl-3-[(1R,3R)-3-[[(dimethylamino)carbonyl]amino]methyl]-3,5,5-trimethylcyclohexyl]urea; (1R,3R)-3-[[(Dimethylamino)carbonyl]amino]methyl]-3,5,5-trimethylcyclohexyl]-1,1-dimethylurea; N-[(1R,3R)-3-[[(Dimethylamino)carbonyl]amino]methyl]-3,5,5-trimethylcyclohexyl]-N',N'-dimethylurea; Desloratadine Related Compound; Desloratadine Impurity; Descarboethoxyloratadine Impurity; Axerane Intermediate
EINECS	Contact for details

Quality Control

Our 3-[(1R,3R)-3-{[(Dimethylcarbamoyl)Amino]Methyl}-3,5,5-Trimethylcyclohexyl]-1,1-Dimethylurea is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with stringent specifications for advanced chemical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (1R,3R isomer)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.