Description

o-Methyl-D-Tyrosine is a non-natural, chiral amino acid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel peptides and bioactive molecules, enabling precise structural modifications. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, particularly for creating metabolically stable analogs and investigating enzyme inhibition. The high purity and defined stereochemistry of this material are essential for ensuring reproducible results in sensitive biochemical applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, including enzyme inhibitors and receptor modulators.
• Peptide Synthesis: Used as a modified tyrosine residue in solid-phase and solution-phase peptide synthesis to alter peptide stability, bioavailability, and activity.
• Biochemical Research: Employed in enzymatic studies and as a standard or probe in metabolic pathway analysis due to its non-natural character.
• Asymmetric Synthesis: Serves as a valuable starting material or auxiliary in the synthesis of complex, enantiomerically pure molecules.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	o-Methyl-D-Tyrosine
CAS No.	132574-59-5
Molecular Formula	C10H13NO3
Molecular Weight	195.22 g/mol
Synonyms	D-2-Methyltyrosine; (R)-2-Amino-3-(2-hydroxy-5-methylphenyl)propanoic acid; (R)-2-Methyltyrosine; H-D-2-MeTyr-OH; D-o-Methyltyrosine; D-2-MT; NSC 339517; D-2-Hydroxy-5-methylphenylalanine
EINECS	Contact for details

Quality Control

Our o-Methyl-D-Tyrosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific results for identity, purity, and related substances is provided with every shipment. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.