Description

2-Amino-2-Methyl-4-Phenylbutanoic Acid Hydrochloride is a high-purity, non-proteinogenic amino acid derivative used as a critical building block in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the development of pharmaceutical actives and bioactive peptides. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for applications in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in protease inhibitor research.
• Peptide Synthesis: Used as a protected amino acid building block in solid-phase and solution-phase peptide chemistry to introduce structural complexity.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and for probing biological pathways.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to construct stereogenic centers.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	2-Amino-2-Methyl-4-Phenylbutanoic Acid Hydrochloride
CAS No.	132539-65-2
Molecular Formula	C11H16ClNO2
Molecular Weight	229.70 g/mol
Synonyms	2-Amino-2-methyl-4-phenylbutyric acid hydrochloride; 2-Methyl-2-amino-4-phenylbutanoic acid HCl; 4-Phenyl-2-aminoisovaleric acid hydrochloride; (R,S)-2-Amino-2-methyl-4-phenylbutanoic acid hydrochloride; 2-Amino-2-methyl-4-phenylbutyrate hydrochloride; α-Methyl-β-phenyl-DL-homoalanine hydrochloride; DL-2-Amino-2-methyl-4-phenylbutanoic acid hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Amino-2-Methyl-4-Phenylbutanoic Acid Hydrochloride is manufactured under a quality management system and undergoes rigorous analytical testing to ensure batch-to-batch consistency and high purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.