Description

tert-Butyloxycarbonyl-α-Aza-(4-Aminophenyl)Alanine Phenyl Ester is a specialized, high-purity protected amino acid derivative designed for advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise, high-yield coupling reactions in complex molecule assembly. It is primarily utilized by the pharmaceutical and biotechnology industries for the development of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).

Application

• Peptide Synthesis: Serves as a key building block (Fmoc/Boc-protected amino acid) in solid-phase and solution-phase peptide synthesis for research and commercial-scale production.
• Pharmaceutical Intermediates: Used in the synthesis of complex peptide drugs, including hormone analogs, enzyme inhibitors, and targeted cancer therapies.
• Proteomics Research: Employed in the design and synthesis of substrate analogs, enzyme inhibitors, and probes for studying protein-protein interactions and enzyme mechanisms.
• Combinatorial Chemistry: A valuable reagent for generating diverse chemical libraries in drug discovery and lead optimization programs.
• Bioconjugation: Facilitates the site-specific modification of peptides and proteins for diagnostic and therapeutic applications.
• Academic & Contract Research: Essential for synthetic chemistry research in academic institutions and contract research organizations (CROs) focused on novel amino acid chemistry.

Basic Information

Product Name	tert-Butyloxycarbonyl-α-Aza-(4-Aminophenyl)Alanine Phenyl Ester
CAS No.	132509-36-5
Molecular Formula	C21H25N3O4
Molecular Weight	383.44 g/mol
Synonyms	Boc-Aza-Phe(4-NH2)-OPh; Boc-α-Aza-(4-aminophenyl)alanine phenyl ester; N-(tert-Butoxycarbonyl)-α-aza-4-aminophenylalanine phenyl ester; Boc-Phe(4-NH2)[CH2N]-OPh; (S)-2-((tert-Butoxycarbonyl)amino)-3-(4-aminophenyl)-2-azapropanoic acid phenyl ester; Protected Aza-Phenylalanine Derivative; Boc-Aza-Tyr(4-NH2)-OPh (common alias)
EINECS	Contact for details

Quality Control

Our tert-Butyloxycarbonyl-α-Aza-(4-Aminophenyl)Alanine Phenyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions or a dry inert atmosphere to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.