Description

(1S,2R)-(-)-2-Aminocyclohex-3-Enecarboxylic Acid Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic value. Its constrained cyclohexene scaffold and defined stereochemistry make it a critical precursor for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for asymmetric synthesis and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, particularly those targeting neurological and metabolic disorders.
• Asymmetric Catalysis Research: Used as a ligand precursor or a model substrate in the development and study of new asymmetric synthetic methodologies.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with enhanced stereoselective activity.
• Peptidomimetics & Conformationally Restricted Peptides: Incorporated into peptide backbones to induce specific secondary structures and improve metabolic stability.
• Academic & Industrial R&D: Employed in chemical biology and medicinal chemistry research for library synthesis and structure-activity relationship (SAR) studies.
• Fine Chemical Production: Used in the multi-step synthesis of advanced chiral compounds for various high-value industrial applications.

Basic Information

Product Name	(1S,2R)-(-)-2-Aminocyclohex-3-Enecarboxylic Acid Hydrochloride
CAS No.	132487-40-2
Molecular Formula	C7H12ClNO2
Molecular Weight	177.63 g/mol
Synonyms	(1S,2R)-2-Amino-3-cyclohexene-1-carboxylic acid hydrochloride; (-)-cis-2-Aminocyclohex-3-ene-1-carboxylic acid hydrochloride; (1S,2R)-2-Aminocyclohex-3-ene-1-carboxylic acid HCl; 2-Amino-1-cyclohexene-1-carboxylic acid hydrochloride (stereospecific); ACCA hydrochloride; Cyclohexene amino acid hydrochloride derivative
EINECS	Contact for details

Quality Control

Our (1S,2R)-(-)-2-Aminocyclohex-3-Enecarboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.