Description

Methyl-3,5-Di-o-Benzyl-D-Threo-Pentafuranoside is a high-purity, protected carbohydrate derivative and a key chiral building block in organic synthesis. This compound matters for its role as a crucial intermediate in the production of complex nucleoside analogs and other biologically active molecules, enabling precise stereochemical control. Pharmaceutical research and development laboratories, particularly those focused on antiviral and anticancer therapeutics, require this specific intermediate for advanced synthetic routes.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel nucleoside and nucleotide analogs with potential antiviral or anticancer activity.
• Antiviral Drug Research: Used in the development of prodrugs and modified nucleosides targeting viral polymerases.
• Carbohydrate Chemistry: Serves as a protected sugar derivative for constructing complex oligosaccharides, glycoconjugates, and glycomimetics.
• Process Chemistry & Scale-up: Employed in the development and optimization of scalable synthetic pathways for active pharmaceutical ingredients (APIs).
• Biochemical Tool Development: Utilized in creating labeled or modified sugars for metabolic studies and enzyme inhibition assays.
• Academic & Contract Research: A valuable reagent for universities and CROs conducting research in medicinal chemistry and chemical biology.

Basic Information

Item	Detail
Product Name	Methyl-3,5-Di-o-Benzyl-D-Threo-Pentafuranoside
CAS No.	132487-16-2
Molecular Formula	C20H24O5
Molecular Weight	344.40 g/mol
Synonyms	1,2-O-Isopropylidene-3,5-di-O-benzyl-α-D-xylofuranose; 3,5-Di-O-benzyl-1,2-O-isopropylidene-α-D-xylofuranose; Methyl 3,5-di-O-benzyl-D-threo-pentofuranoside; D-Threo-Pentofuranoside, methyl 3,5-di-O-benzyl-; Protected D-xylofuranose derivative; Benzyl-protected pentofuranoside
EINECS	Contact for details

Quality Control

Our Methyl-3,5-Di-o-Benzyl-D-Threo-Pentafuranoside is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is moisture-sensitive; ensure the container is kept sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.