Description

3-Amino-α-Methyl-4-(2-Thiazolyl)Benzeneacetic Acid is a high-purity, non-steroidal anti-inflammatory drug (NSAID) intermediate of significant commercial importance. This compound serves as a critical building block in the synthesis of advanced pharmaceutical actives, where its structural integrity directly impacts final product efficacy and safety. It is primarily required by manufacturers in the pharmaceutical and fine chemical sectors for research, development, and large-scale production processes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of specific non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents.
• Fine Chemical Synthesis: Used as a versatile building block for constructing complex organic molecules in research and development.
• Biochemical Research: Employed in studies targeting enzyme inhibition and the development of new anti-inflammatory pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory submissions.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry and drug discovery programs.

Basic Information

Product Name	3-Amino-α-Methyl-4-(2-Thiazolyl)Benzeneacetic Acid
CAS No.	132483-60-4
Molecular Formula	C₁₃H₁₂N₂O₂S
Molecular Weight	260.31 g/mol
Synonyms	3-Amino-α-methyl-4-(2-thiazolyl)benzeneacetic acid; 2-(3-Amino-4-(thiazol-2-yl)phenyl)propanoic acid; Amtolmetin guacil intermediate; 2-[3-Amino-4-(1,3-thiazol-2-yl)phenyl]propanoic acid; α-Methyl-3-amino-4-(2-thiazolyl)benzeneacetic acid; 4-(2-Thiazolyl)-3-amino-α-methylbenzeneacetic acid; ATMG intermediate; NSC 339586
EINECS	Contact for details

Quality Control

Our 3-Amino-α-Methyl-4-(2-Thiazolyl)Benzeneacetic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.