Description

α-Methyl-4-(5-Methyl-2-Thiazolyl)Benzeneacetic Acid CAS NO 132483-43-3 is a high-purity, non-steroidal anti-inflammatory drug (NSAID) intermediate, specifically a thiazole-substituted arylacetic acid derivative. This compound is of critical importance for the synthesis of advanced pharmaceutical actives, offering a precise chemical scaffold for targeted drug development. It is primarily required by research institutions and manufacturers in the pharmaceutical and fine chemical sectors engaged in developing new analgesic and anti-inflammatory agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel NSAIDs and other therapeutic agents targeting inflammation and pain.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new drug candidates.
• Fine Chemical Synthesis: Serves as a precursor for more complex molecules in custom synthesis and contract manufacturing.
• Biochemical Research: Potential tool compound for studying cyclooxygenase (COX) enzyme pathways and related biochemical mechanisms.

Basic Information

Product Name	α-Methyl-4-(5-Methyl-2-Thiazolyl)Benzeneacetic Acid
CAS No.	132483-43-3
Molecular Formula	C₁₃H₁₃NO₂S
Molecular Weight	247.31 g/mol
Synonyms	2-(4-(5-Methylthiazol-2-yl)phenyl)propanoic acid; α-Methyl-4-(5-methyl-2-thiazolyl)benzeneacetic acid; 4-(5-Methyl-2-thiazolyl)-α-methylbenzeneacetic acid; 2-[4-(5-Methyl-1,3-thiazol-2-yl)phenyl]propanoic acid; 2-(4-(5-Methylthiazol-2-yl)phenyl)propionic acid; (RS)-2-(4-(5-Methylthiazol-2-yl)phenyl)propanoic acid
EINECS	Contact for details

Quality Control

Our α-Methyl-4-(5-Methyl-2-Thiazolyl)Benzeneacetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and reliable batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.