Description

tert-Butyl(2S)-2-{[(Methylsulfonyl)Oxy]Methyl}-Pyrrolidine-1-Carboxylate is a high-purity, chiral building block and key synthetic intermediate of significant importance in advanced organic synthesis. Its core value lies in providing a protected, activated pyrrolidine scaffold essential for constructing complex molecules with precise stereochemistry. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of complex drug candidates, particularly those targeting the central nervous system (CNS).
• Agrochemical Synthesis: Used in the research and development of novel, stereospecific pesticides and herbicides.
• Asymmetric Catalysis: Serves as a ligand precursor or a chiral auxiliary in catalytic reactions to induce enantioselectivity.
• Peptidomimetics & Proline Derivatives: Acts as a key building block for creating proline-based peptidomimetics and modified amino acid analogs.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and enzyme function.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high stereochemical purity.

Basic Information

Product Name	tert-Butyl(2S)-2-{[(Methylsulfonyl)Oxy]Methyl}-Pyrrolidine-1-Carboxylate
CAS No.	132482-09-8
Molecular Formula	C12H23NO5S
Molecular Weight	293.38 g/mol
Synonyms	1-Boc-2-(methanesulfonyloxymethyl)pyrrolidine (S)-; (S)-1-(tert-Butoxycarbonyl)-2-((methylsulfonyloxy)methyl)pyrrolidine; (S)-tert-Butyl 2-((methylsulfonyloxy)methyl)pyrrolidine-1-carboxylate; (2S)-1-[(2-Methyl-2-propanyl)oxycarbonyl]-2-[(methylsulfonyl)oxy]methyl]pyrrolidine; (S)-1-Boc-2-(mesyloxymethyl)pyrrolidine; tert-Butyl (2S)-2-(mesyloxymethyl)pyrrolidine-1-carboxylate; BOC-L-Proline Mesylate Ester Derivative
EINECS	Contact for details

Quality Control

Our tert-Butyl(2S)-2-{[(Methylsulfonyl)Oxy]Methyl}-Pyrrolidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee traceability and batch-to-batch consistency for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen) after opening to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.