Description

tert-Butyl (2R)-2-(2-Hydroxyethyl)pyrrolidine-1-carboxylate is a high-purity chiral building block and Boc-protected amino alcohol derivative. This compound is critical for the synthesis of complex molecules where stereochemical integrity and functional group compatibility are paramount. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of drug candidates, particularly for neurological and cardiovascular targets.
• Peptide Mimetics & PROTACs: Serves as a versatile scaffold for constructing peptide-like structures and linkers in proteolysis-targeting chimeras (PROTACs).
• Agrochemical Synthesis: Used in the research and development of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Ligand & Catalyst Development: Employed as a precursor for creating chiral ligands and organocatalysts used in enantioselective transformations.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and material science laboratories.

Basic Information

Product Name	tert-Butyl (2R)-2-(2-Hydroxyethyl)pyrrolidine-1-carboxylate
CAS No.	132482-06-5
Molecular Formula	C11H21NO3
Molecular Weight	215.29 g/mol
Synonyms	1-Boc-2-(2-hydroxyethyl)-(2R)-pyrrolidine; (R)-1-(tert-Butoxycarbonyl)-2-(2-hydroxyethyl)pyrrolidine; (R)-tert-Butyl 2-(2-hydroxyethyl)pyrrolidine-1-carboxylate; (2R)-1-[(tert-Butoxy)carbonyl]-2-(2-hydroxyethyl)pyrrolidine; (R)-2-(2-Hydroxyethyl)-1-Boc-pyrrolidine; (R)-N-Boc-2-(2-hydroxyethyl)pyrrolidine; (R)-1-Boc-2-(2-hydroxyethyl)pyrrolidine; Boc-(R)-2-(2-Hydroxyethyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our tert-Butyl (2R)-2-(2-Hydroxyethyl)pyrrolidine-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high enantiomeric purity and chemical identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.