Description

5,6,7,8-Tetrahydro[1,2,4]Triazolo[1,5-A]Pyridin-8-Amine is a high-value, nitrogen-rich heterocyclic building block of significant interest in advanced organic synthesis. Its fused triazolo-pyridine core structure makes it a critical intermediate for developing novel pharmacologically active compounds. This versatile chemical is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key scaffold in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used extensively in high-throughput screening and structure-activity relationship (SAR) studies to optimize lead compounds.
• Agrochemical Synthesis: Employed as a building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Utilized in the synthesis of specialized ligands for metal catalysis and in the preparation of organocatalysts.
• Material Science Precursor: Acts as a precursor for nitrogen-doped carbon materials or as a monomer for specialty polymers.

Basic Information

Product Name	5,6,7,8-Tetrahydro[1,2,4]Triazolo[1,5-A]Pyridin-8-Amine
CAS No.	132454-36-5
Molecular Formula	C6H10N4
Molecular Weight	138.17 g/mol
Synonyms	8-Amino-5,6,7,8-tetrahydro[1,2,4]triazolo[1,5-a]pyridine; 5,6,7,8-Tetrahydro-[1,2,4]triazolo[1,5-a]pyridin-8-amine; THTP-8-Amine; Triazolopyridinamine derivative; 1,2,4-Triazolo[1,5-a]pyridin-8-amine, 5,6,7,8-tetrahydro-; 132454-36-5
EINECS	Contact for details

Quality Control

Our 5,6,7,8-Tetrahydro[1,2,4]Triazolo[1,5-A]Pyridin-8-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.