Description

Pregn-5-En-3-Ol, 20-Methyl-21-(2-Methyl-3-(1-Methylethyl)Cyclopropyl)- , (3Beta,20R,21(1R,2R,3S))- is a high-purity, stereochemically defined steroid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical advanced intermediate or reference standard for the synthesis of novel therapeutic agents targeting hormonal pathways and metabolic disorders. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing next-generation steroid-based drugs.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel steroid-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used in analytical method development and validation for quality control of related steroid compounds.
• Biochemical Research: Employed in studies investigating steroid receptor interactions, enzyme inhibition, and metabolic pathways.
• Process Chemistry: Serves as a starting material or intermediate in the development of scalable synthetic routes for complex steroid molecules.
• Academic Research: Utilized in universities and research institutes for exploring new chemical entities and their biological activities.

Basic Information

Product Name	Pregn-5-En-3-Ol, 20-Methyl-21-(2-Methyl-3-(1-Methylethyl)Cyclopropyl)- , (3Beta,20R,21(1R,2R,3S))-
CAS No.	132438-14-3
Molecular Formula	C28H46O
Molecular Weight	398.67 g/mol
Synonyms	(20R,21R)-20-Methyl-21-(2-methyl-3-isopropylcyclopropyl)pregn-5-en-3β-ol; 20-Methyl-21-(2-methyl-3-isopropylcyclopropyl)pregn-5-en-3β-ol; 3β-Hydroxy-20-methyl-21-(2-methyl-3-isopropylcyclopropyl)pregn-5-ene; A steroidal cyclopropane derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems. Each batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support development and cGMP-grade requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.