Description

tert-Butyl 1-Benzylhexahydropyrrolo[3,4-B]Pyrrole-5(1H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex, fused bicyclic pyrrolidine-pyrrole scaffold. This compound is of critical importance for its role as a key building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing novel compound libraries in hit-to-lead and lead optimization programs.
• Protease Inhibitor Development: The bicyclic amine structure is valuable for creating potent inhibitors targeting specific proteases.
• CNS Drug Discovery: Employed in the research and development of potential therapeutics for neurological and psychiatric disorders.
• Chemical Biology Probes: Utilized to develop tool compounds for studying biological pathways and target validation.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke molecules for clients.

Basic Information

Product Name	tert-Butyl 1-Benzylhexahydropyrrolo[3,4-B]Pyrrole-5(1H)-Carboxylate
CAS No.	132414-80-3
Molecular Formula	C18H26N2O2
Molecular Weight	302.41 g/mol
Synonyms	1-Benzyl-5-(tert-butoxycarbonyl)hexahydropyrrolo[3,4-b]pyrrole; tert-Butyl 1-benzyl-2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-b]pyrrole-5-carboxylate; 1H-Pyrrolo[3,4-b]pyrrole-5-carboxylic acid, 2,3,3a,4,6,6a-hexahydro-1-(phenylmethyl)-, 1,1-dimethylethyl ester; 1-Benzyl-5-Boc-hexahydropyrrolo[3,4-b]pyrrole; BOC-1-Benzyl-hexahydropyrrolo[3,4-b]pyrrole
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-Benzylhexahydropyrrolo[3,4-B]Pyrrole-5(1H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.