Description

5-Methyl-1H-hexahydropyrrolo[3,4-b]pyrrole is a high-purity, bicyclic nitrogen-containing heterocycle that serves as a critical advanced intermediate in modern organic synthesis. This compound matters because it provides a versatile and structurally constrained scaffold essential for constructing complex pharmacophores. Pharmaceutical R&D and fine chemical manufacturers need this building block for developing novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas like central nervous system (CNS) disorders and oncology.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially those targeting neurological receptors.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides that require specific heterocyclic frameworks.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Investigated as a monomer or additive in the creation of specialty polymers with unique electronic or binding properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and protein-protein interactions.

Basic Information

Product Name	5-Methyl-1H-hexahydropyrrolo[3,4-b]pyrrole
CAS No.	132414-59-6
Molecular Formula	C8H14N2
Molecular Weight	138.21 g/mol
Synonyms	5-Methylhexahydropyrrolo[3,4-b]pyrrole; 5-Methyl-1H,2H,3H,3aH,6H,6aH-pyrrolo[3,4-b]pyrrole; 5-Methyloctahydropyrrolo[3,4-b]pyrrole; 1H-Hexahydropyrrolo[3,4-b]pyrrole, 5-methyl-; 5-Methyl-1H,2H,3H,3aH,6H,6aH-pyrrolo[3,4-b]pyrrole; 5-Methyl-2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-b]pyrrole
EINECS	Contact for details

Quality Control

Our 5-Methyl-1H-hexahydropyrrolo[3,4-b]pyrrole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC and GC analysis, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.