Description

(2R)-3-Methyl-2-{[(Prop-2-En-1-Yloxy)Carbonyl]Amino}Butanoic Acid is a high-purity, chiral amino acid derivative of significant value in advanced organic synthesis. This compound matters as a critical building block for the development of novel pharmaceuticals and bioactive molecules, offering precise stereochemical control. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in peptide synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for protease inhibitors and other targeted therapies.
• Peptide Synthesis: Serves as a protected amino acid derivative for solid-phase and solution-phase peptide synthesis, enabling the incorporation of the valine side chain with specific stereochemistry.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and as a scaffold for creating compound libraries in drug discovery programs.
• Agrochemical Development: Employed in the synthesis of chiral herbicides, fungicides, and plant growth regulators where specific stereoisomers exhibit enhanced biological activity.
• Bioconjugation & Linker Chemistry: The allyloxycarbonyl (Alloc) protecting group makes it valuable for orthogonal deprotection strategies in complex multi-step syntheses and bioconjugation techniques.
• Catalyst & Ligand Preparation: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	(2R)-3-Methyl-2-{[(Prop-2-En-1-Yloxy)Carbonyl]Amino}Butanoic Acid
CAS No.	132402-46-1
Molecular Formula	C9H15NO4
Molecular Weight	201.22 g/mol
Synonyms	N-Alloc-D-valine; D-Valine, N-[(2-propen-1-yloxy)carbonyl]-; (R)-2-((Allyloxycarbonyl)amino)-3-methylbutanoic acid; N-Alloc-D-val-OH; Alloc-D-Valine; (2R)-3-Methyl-2-[(prop-2-en-1-yloxycarbonyl)amino]butanoic acid; N-(Allyloxycarbonyl)-D-valine; ALLOC-D-VAL
EINECS	Contact for details

Quality Control

Our (2R)-3-Methyl-2-{[(Prop-2-En-1-Yloxy)Carbonyl]Amino}Butanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with stringent specifications for research and production use. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.