Description

(S)-2-Phenethylpiperidine Hydrochloride is a high-purity chiral building block and intermediate of significant interest in advanced organic synthesis. Its value lies in its stereochemically defined piperidine scaffold, which is a privileged structure in medicinal chemistry for modulating biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating novel active ingredients for central nervous system (CNS) targets, pain management, and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of potential drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used as a scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Intermediate in the research and synthesis of novel crop protection agents and pesticides.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Chemical Biology Probes: Building block for creating molecular probes to study enzyme function and biological pathways.
• Academic & Institutional R&D: Used in university and research institute laboratories for fundamental studies in organic and heterocyclic chemistry.

Basic Information

Product Name	(S)-2-Phenethylpiperidine Hydrochloride
CAS No.	132363-97-4
Molecular Formula	C13H20ClN
Molecular Weight	225.76 g/mol
Synonyms	(S)-2-(2-Phenylethyl)piperidine hydrochloride; (S)-2-Phenethylpiperidine HCl; (S)-α-Phenethylpiperidine hydrochloride; (2S)-2-(2-Phenylethyl)piperidine hydrochloride; (S)-1-(2-Phenylethyl)piperidine-2-carboxylic acid hydrochloride (related); Piperidine, 2-(2-phenylethyl)-, hydrochloride, (2S)-
EINECS	Contact for details

Quality Control

Our (S)-2-Phenethylpiperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profiles is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.