Description

(4S)-Hexahydro-6α-Hydroxy-4α-(Hydroxymethyl)-7α-Methylcyclopenta[C]Pyran-3(4H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry. This compound is valued for its role as a critical building block in the synthesis of complex, biologically active molecules, offering precise structural control. It is primarily required by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of proprietary drug candidates, particularly in steroid and terpenoid-related synthetic pathways.
• Organic Synthesis Building Block: Utilized in academic and industrial R&D for constructing complex polycyclic frameworks due to its functionalized cyclopentapyran structure.
• Process Chemistry: Serves as a starting material or intermediate in scalable process development for active pharmaceutical ingredients (APIs).
• Asymmetric Catalysis Studies: Employed as a substrate or ligand precursor in the development and testing of new asymmetric synthetic methodologies.

Basic Information

Product Name	(4S)-Hexahydro-6α-Hydroxy-4α-(Hydroxymethyl)-7α-Methylcyclopenta[C]Pyran-3(4H)-One
CAS No.	132339-37-8
Molecular Formula	C10H16O4
Molecular Weight	200.23 g/mol
Synonyms	(4S)-Hexahydro-6α-hydroxy-4α-(hydroxymethyl)-7α-methylcyclopenta[c]pyran-3(4H)-one; (4S,4aS,6aR,7aS)-Hexahydro-6a-hydroxy-4a-(hydroxymethyl)-7a-methylcyclopenta[c]pyran-3(4H)-one; 6α-Hydroxy-4α-(hydroxymethyl)-7α-methyl-4S-cyclopenta[c]pyran-3-one; A key intermediate for prostaglandin synthesis; Chiral cyclopentapyranone derivative.
EINECS	Contact for details

Quality Control

Our (4S)-Hexahydro-6α-Hydroxy-4α-(Hydroxymethyl)-7α-Methylcyclopenta[C]Pyran-3(4H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccated environment after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.