Description

(R)-3-(Dimethylamino)-1-(Thiophen-2-Yl)Propan-1-Ol is a chiral amino alcohol building block of significant importance in asymmetric synthesis and pharmaceutical development. Its core value lies in its stereochemistry, which is critical for imparting specific biological activity in active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity chiral intermediates for the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure drug candidates, particularly those targeting the central nervous system.
• Asymmetric Catalyst Ligand: Used in the preparation of chiral ligands for metal-catalyzed reactions, such as hydrogenation or alkylation.
• Agrochemical Synthesis: Serves as a building block for the development of chiral pesticides and herbicides with enhanced efficacy and selectivity.
• Fine Chemical Production: Employed in the multi-step synthesis of complex natural products and specialty chemicals requiring precise stereocontrol.
• Research & Development: A valuable standard and reagent in academic and industrial R&D labs for method development and exploring new synthetic pathways.

Basic Information

Product Name	(R)-3-(Dimethylamino)-1-(Thiophen-2-Yl)Propan-1-Ol
CAS No.	132335-49-0
Molecular Formula	C9H15NOS
Molecular Weight	185.29 g/mol
Synonyms	(R)-3-(Dimethylamino)-1-(2-thienyl)-1-propanol; (R)-1-(2-Thienyl)-3-(dimethylamino)-1-propanol; (R)-N,N-Dimethyl-3-(2-thienyl)-3-hydroxypropylamine; (R)-Thiophene-2-ethanol, 3-(dimethylamino)-; (R)-Duloxetine Intermediate; (R)-LY248686 Intermediate
EINECS	Contact for details

Quality Control

Our (R)-3-(Dimethylamino)-1-(Thiophen-2-Yl)Propan-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with customer specifications and industry standards. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.