Description

S-(+)-N,n-Dimethyl-3-(1-Naphthoxy)-3-(2-Thienyl)-1-Propylamine Oxalate is a high-purity, chiral organic compound primarily utilized as a key intermediate in advanced pharmaceutical synthesis. Its specific stereochemistry and complex molecular architecture make it valuable for research and development of novel active pharmaceutical ingredients (APIs). This compound is particularly relevant for organizations engaged in the development of central nervous system (CNS) agents and other specialized therapeutics, where precise molecular configuration is critical for biological activity.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of novel drug candidates, particularly for neurological and psychiatric applications.
• Research & Development: Used in medicinal chemistry research for structure-activity relationship (SAR) studies and the development of new chemical entities.
• Asymmetric Synthesis: Employed as a reagent or precursor in stereoselective synthesis to create enantiomerically pure compounds.
• Reference Standard: Functions as a high-purity analytical standard for method development and quality control in pharmaceutical laboratories.
• Biochemical Research: Investigated for interactions with biological targets such as neurotransmitter transporters and receptors.
• Process Chemistry: Used in the scale-up and optimization of synthetic routes for complex organic molecules in pilot plant settings.

Basic Information

Product Name	S-(+)-N,n-Dimethyl-3-(1-Naphthoxy)-3-(2-Thienyl)-1-Propylamine Oxalate
CAS No.	132335-47-8
Molecular Formula	C22H25NO5S
Molecular Weight	415.50 g/mol
Synonyms	S-(+)-Duloxetine Impurity; (S)-Duloxetine Related Compound A; (S)-N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)-1-propanamine Oxalate; (S)-N-Methyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine Oxalate; LY248686 Oxalate Salt (S-enantiomer); (S)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine Oxalate
EINECS	Contact for details

Quality Control

Our S-(+)-N,n-Dimethyl-3-(1-Naphthoxy)-3-(2-Thienyl)-1-Propylamine Oxalate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets stringent specifications for pharmaceutical R&D use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (S-enantiomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.