Description

(R)-1-Phenylbut-3-En-1-Amine Hydrochloride CAS NO 132312-93-7 is a high-purity chiral amine hydrochloride salt, serving as a critical building block in advanced organic synthesis. Its enantiopure nature and stable salt form make it an indispensable intermediate for the development of active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with specific stereochemical requirements.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in the research and production of chiral pesticides and herbicides, where stereochemistry influences biological activity.
• Catalyst and Ligand Preparation: Serves as a starting material for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific enantiomeric forms.
• Academic and R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research within universities and corporate labs.
• Material Science: Potential monomer or precursor for advanced polymeric materials with specific chiral properties.

Basic Information

Product Name	(R)-1-Phenylbut-3-En-1-Amine Hydrochloride
CAS No.	132312-93-7
Molecular Formula	C10H14ClN
Molecular Weight	183.68 g/mol
Synonyms	(R)-1-Amino-1-phenyl-3-butene hydrochloride; (R)-1-Phenyl-3-buten-1-amine hydrochloride; (R)-α-Methylbenzylallylamine hydrochloride; (R)-1-Phenylbut-3-enylamine hydrochloride; (R)-4-Phenyl-3-buten-1-amine hydrochloride; (R)-1-Phenyl-3-butenamine hydrochloride; (R)-1-Phenylbut-3-en-1-amine HCl
EINECS	Contact for details

Quality Control

Our (R)-1-Phenylbut-3-En-1-Amine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, NMR for structural confirmation, and titration for assay. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our customers' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.