Description

(2S,3S)-2,3-Bis(Benzoyloxymethyl)Cyclobutanone is a high-purity, stereochemically defined chiral synthon of significant interest in advanced organic synthesis. Its value lies in its rigid cyclobutanone core functionalized with benzoyl-protected hydroxymethyl groups, making it a versatile building block for constructing complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug candidates, particularly those requiring specific stereochemistry for biological activity.
• Agrochemical Research: Used in the development of novel pesticides and herbicides where the cyclobutanone scaffold imparts unique biological properties.
• Material Science: Serves as a monomer or cross-linking agent in the research of specialty polymers with tailored thermal or mechanical properties.
• Asymmetric Synthesis: Employed as a starting material or chiral auxiliary in catalytic asymmetric reactions to induce high enantioselectivity.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms or protein interactions.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and process chemistry optimization.

Basic Information

Product Name	(2S,3S)-2,3-Bis(Benzoyloxymethyl)Cyclobutanone
CAS No.	132294-16-7
Molecular Formula	C22H22O5
Molecular Weight	366.41 g/mol
Synonyms	(2S,3S)-2,3-Bis(benzoyloxymethyl)cyclobutan-1-one; (2S,3S)-2,3-Bis[(benzoyloxy)methyl]cyclobutanone; 1,2-Bis(hydroxymethyl)cyclobutanone dibenzoate (stereospecific); (2S-cis)-2,3-Bis[(benzoyloxy)methyl]cyclobutanone; Cyclobutanone, 2,3-bis(benzoyloxymethyl)-, (2S,3S)-; BOCB (abbreviation); Chiral Cyclobutanone Dibenzoate; 132294-16-7
EINECS	Contact for details

Quality Control

Our (2S,3S)-2,3-Bis(Benzoyloxymethyl)Cyclobutanone is manufactured under strict quality control protocols to ensure high chemical and chiral purity suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, enantiomeric excess, and impurity profile. We are committed to supply chain transparency and batch-to-batch consistency to support your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.