Description

Tetrahydropyran-4-Ylmethyl Methanesulfonate is a versatile organic building block and key intermediate in advanced chemical synthesis. Its value lies in its reactive methanesulfonate (mesylate) group, which serves as an excellent leaving group for nucleophilic substitution reactions, enabling the efficient introduction of the tetrahydropyranylmethyl moiety. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and novel molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry for creating molecules with complex heterocyclic structures.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the tetrahydropyran scaffold imparts specific biological activity.
• Organic Synthesis Reagent: Serves as an alkylating agent in complex organic transformations, facilitating carbon-carbon and carbon-heteroatom bond formation in fine chemical production.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organocatalysts for asymmetric synthesis and other catalytic processes.
• Material Science Research: Used as a monomer or functionalization agent in the development of novel polymers and advanced functional materials.

Basic Information

Product Name	Tetrahydropyran-4-Ylmethyl Methanesulfonate
CAS No.	132291-95-3
Molecular Formula	C8H16O4S
Molecular Weight	208.28 g/mol
Synonyms	4-(Methanesulfonyloxymethyl)tetrahydropyran; (Oxan-4-yl)methyl methanesulfonate; THP-4-ylmethyl mesylate; Tetrahydropyran-4-ylmethyl mesylate; 4-(Methylsulfonyloxymethyl)tetrahydropyran; (Tetrahydropyran-4-yl)methyl methanesulfonate; 132291-95-3; 4-(Methanesulfonyloxy)methyltetrahydropyran
EINECS	Contact for details

Quality Control

Our Tetrahydropyran-4-Ylmethyl Methanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopic methods, to ensure high purity and consistency suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.